Home About Archives RSS Feed

New Biotech Firm Setting Up in Pittsfield

PITTSFIELD, Mass. — A new biotechnology firm, Molecular Metabolism LLC, born out of a relationship with Nuclea Biotechnologies, has chosen Pittsfield as its  headquarters.

Molecular Metabolism is in the process of assembling its management team and is expected to create seven to 10 new jobs locally.

It is a development stage company focused on the discovery of biomarkers and therapeutic-based targets for metabolic syndromes and central nervous system (CNS) diseases. These biomarkers can aid physicians in determining the best, individualized courses of treatment for patients suffering from metabolic conditions, such as obesity, fatty liver disease and diabetes.

Molecular Metabolism and Nuclea Biotechnologies have established a collaboration with Joslin Diabetes Center, the diabetes research and care organization affiliated with Harvard Medical School, in biomarkers of insulin resistance and applications of imaging. The initial research in imaging will help identify "brown fat" in humans, a type of fat that drives energy expenditure and may potentially benefit metabolic endpoints.

Molecular Metabolism's collaboration with Joslin will assess the feasibility of using MRI and Infrared thermal imaging to measure the mass and activity of cold-activated human brown adipose tissues (BAT). The partners believe that the results of this research will provide greater insight into how Type 2 diabetes is evaluated and diagnosed with the goal of screening new therapies that stimulate generation of brown fat.  This work will be done with Dr. Aaron Cypess, assistant professor and investigator at Joslin Diabetes Center.

"Diagnostics and imaging techniques can make a significant impact on the detection and management of diabetes and its complications, and Joslin’s interest in brown fat stimulation and energy expenditure is an exciting area to apply this to," said Cypess. "We hope to advance our techniques to a stage where brown fat can be easily detected and quantified."

Patrick Muraca, interim president of Molecular Metabolism and president and CEO of Nuclea Biotechnologies, said, "Molecular Metabolism will collaborate with Nuclea in the research and development of the biomarkers. Joslin is a tremendous partner and I believe this research in brown fat imaging will help us as we work to create new tools for the treatment and diagnosis of Type 2 diabetes."

Joslin will also work with Nuclea Biotechnologies, under the direction of Dr. Mary Elizabeth Patti, assistant professor and investigator at Joslin, to apply proteomic analyses on patient cohorts in order to understand pathways leading to insulin resistance and develop biomarkers of risk of Type 2 diabetes.

"We are very pleased to be partnering with Nuclea to identify new biomarkers which could potentially be used to determine risk of diabetes and other metabolic disease," said Patti. "These efforts are crucial in the fight against diabetes, so that we can identify those individuals at the highest risk of disease, and also to individualize optimal treatment strategies."

News Headlines
Williams' Softball Team Rallies to Top Chicago in Extra Innings
Pittsfield's Lakeway Drive Bridge Set for 2020 Replacement
Northern Berkshire Youth Baseball Assigns New Players to Teams
VA Hosting Agent Orange Town Hall in Pittsfield
Gabriel Abbott Announces Second Trimester Honor Roll
North Adams Awarded State Grant for Eagle St. Business Development
North Adams Happenings: March 21-27
Time for Financial 'Spring Cleaning'
Boys and Girls Club 5th/6th Grade Boys Finish Successful Season
Grady, Taconic's Vosburgh Named Finalists for Mount Greylock Superintendent


Bill Schmick separates the bull from the bears in his weekly columns on investing and market wrap-ups.

advertising (10)
agriculture (1)
arts (7)
automotive (5)
awards (16)
banking (41)
Beacon (1)
broadband (1)
business (52)
chamber (25)
closing (5)
development (23)
dining (5)
domestic animals (2)
energy (6)
entertainment (2)
federal (4)
finances (5)
food (5)
fundraiser (3)
green (2)
grocery (5)
hospitality/hotel (5)
housing (0)
insurance (3)
investment (6)
jobs (35)
labor (17)
laws (4)
Legislature (3)
manufacturing (9)
media (8)
medical (4)
networking (33)
new (22)
pricing (1)
projects (2)
promotion (6)
publishing (13)
radio (2)
real estate (8)
retail (29)
technology (13)
training (5)
transportation (1)
volunteer (1)
website (2)
wholesale (7)
workshops (6)
Social Media Breakfast Berkshire Living Flood Small Business Unemployment Gas Prices Great Barrington North Adams Baldwin Walmart Berkshire Enterprises Crane & Co. Wmeco Bj's Sales Tax Expansion Auction Sabic Currency Statistics Statistics Berkshire Creative Talkberkshires Pittsfield Excelsior Store Opening Unemployment Qualprint Jobs Williamstown Berkshire Chamber Of Commerce State Adams Merger
Popular Entries:
Excelsior Brings Greeting Card Co. To North Adams
Berkshire Jobless Rates Drop
Bay State Continues to Add Jobs
Williamstown Chamber Seeks Input on Future Role
Aladco Installs New 'Green' Washing Machine
Storey Publishing to Host Next Creative Challenge
New Dog Training Center Open in North Adams
White Hart Inn For Sale for $5M
Carbone Dealership Empties Lot
Real Estate Panel to Tour S. County, Pittsfield Sites
Recent Entries:
Biz Briefs: Mr. Tire, Tax Holiday, Business Directory
Berkshire Eagle Parent Mulling Newspaper Sales
Digitial First Puts Vermont News Buildings on the Market
Berkshire Chamber, Neal Hosting Facebook for Business Workshop
Winstanley Wins Big at Annual ADDY Awards
Eggs & Issues Event Focuses on Rail Cars, Development
State Unemployement Rate Drops Slightly
New Biotech Firm Setting Up in Pittsfield
Crane Museum Opens Retail Store
License Commission Approves River Street Package Move